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Issue file · proposed
NIH and FDA New Approach Methodologies (NAMs) and microphysiological systems funding to replace animal testing
Federal funding opportunities and policy for NIH-supported microphysiological systems (organ-on-chip) and other New Approach Methodologies, including NIAID translational centers for infectious diseases, FDA acceptance and validation of NAMs, and the shift away from animal testing in biomedical research and drug development.
Biotech
- Earliest seen
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- No coverage yet
- Articles · 30d
- 0
- No coverage
- Outlets
- 0
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- Hill · 30d
- 0
- None in 30 days or ahead
- Contracts · 30d
- 5
- 3 open
- Momentum
- 1.3
- Articles ±0 vs prior week
Activity
30 days back, 14 ahead · hollow = scheduledWhat's happening
Updated 6d agoNIH has scheduled grant notices on Grants.gov, led by an RFA for consortium Translational Centers using Microphysiological Systems for Infectious Diseases (RFA-AI-28-012, $7M ceiling) dated 2027-01-29. Two other NIH notices follow: a U19 systems biology program on infection, inflammation and chronic disease ($26M ceiling, 2027-02-18) and a translational genome editing/biologic therapy program for Alzheimer's-related dementias ($6M ceiling, 2028-10-10). The items show no recent legislative, FDA or oversight activity.
Hill
No policymaker activity in the window.
Contracts
3 contractsNIH has three upcoming Grants.gov notices: the $7M MPS infectious disease translational centers RFA (2027-01-29), a $26M U19 systems biology program (2027-02-18), and a $6M Alzheimer's-related dementias genome editing program (2028-10-10).
- Open solicitations
- 3
Pressure
No outside pressure in the window.
Who covered it, when
A dot per article · ringed = earliest in our sourcesNo coverage in the last 30 days.
Forces at work
share of articles- Procurement & funding3 · 100%NIH has scheduled the MPS-focused infectious disease translational centers RFA (RFA-AI-28-012, $7M ceiling, 2027-01-29), which reflects NIH and FDA support for New Approach Methodologies including in vitro human tissue systems. Related notices include a $26M U19 and a $6M Alzheimer's-related dementias program.NIH · NIAID
What's next
Times ETGrantNational Institutes of HealthOct 29NIH seeks applications for Genomic Data Generation Center(s) for the Gabriella Miller Kids First Pediatric Research Program, with a $6 million ceiling and responses due January 8, 2027.$6M ceilingCloses in 54 daysRFA-RM-27-008BiotechLifecycle11 linked GrantNational Institutes of HealthOct 20NIH seeks applications to continue the Immune Tolerance Network for tolerogenic therapy clinical trials, with a $27 million ceiling.$27M ceilingCloses in 75 daysRFA-AI-28-005BiotechLifecycle11 linked GrantNational Institutes of HealthOct 20NIH seeks applications for consortium Translational Centers using Microphysiological Systems for Infectious Diseases (RFA-AI-28-012), with a $7M ceiling.$7M ceilingCloses in 75 daysRFA-AI-28-012BiotechLifecycle14 linked GrantNational Institutes of HealthOct 16NIH National Library of Medicine seeks applications for T15 institutional training programs in biomedical informatics, data science, and AI/ML, with a $17.1M ceiling.$17.1M ceilingCloses in 88 daysRFA-LM-28-001BiotechLifecycle14 linked GrantNational Institutes of HealthOct 13NIH seeks applications for research and preclinical development of next-generation malaria vaccines under RFA-AI-28-024, with a $4 million ceiling.$4M ceilingCloses in 88 daysRFA-AI-28-024 (R61/R33 Clinical Trial Not Allowed)BiotechLifecycle12 linked GrantNational Institutes of Health11d agoNIH seeks applications for a U19 systems biology program on infection, inflammation and chronic disease, with a $26 million ceiling.$26M ceilingCloses in 95 daysRFA-AI-28-014BiotechLifecycle12 linked GrantNational Institutes of Health12d agoNIH seeks applications for translational genome editing and biologic therapy development for Alzheimer's-related dementias, with a $6 million ceiling.$6M ceilingCloses in 694 daysRFA-NS-28-012BiotechLifecycle12 linked
In the news
0 articlesNo coverage yet.
Contracts
7GrantNational Institutes of Health12d agoNIH seeks applications for translational genome editing and biologic therapy development for Alzheimer's-related dementias, with a $6 million ceiling.$6M ceilingCloses in 694 daysRFA-NS-28-012BiotechLifecycle12 linked GrantNational Institutes of Health11d agoNIH seeks applications for a U19 systems biology program on infection, inflammation and chronic disease, with a $26 million ceiling.$26M ceilingCloses in 95 daysRFA-AI-28-014BiotechLifecycle12 linked GrantNational Institutes of HealthOct 16NIH National Library of Medicine seeks applications for T15 institutional training programs in biomedical informatics, data science, and AI/ML, with a $17.1M ceiling.$17.1M ceilingCloses in 88 daysRFA-LM-28-001BiotechLifecycle14 linked GrantNational Institutes of HealthOct 13NIH seeks applications for research and preclinical development of next-generation malaria vaccines under RFA-AI-28-024, with a $4 million ceiling.$4M ceilingCloses in 88 daysRFA-AI-28-024 (R61/R33 Clinical Trial Not Allowed)BiotechLifecycle12 linked GrantNational Institutes of HealthOct 20NIH seeks applications to continue the Immune Tolerance Network for tolerogenic therapy clinical trials, with a $27 million ceiling.$27M ceilingCloses in 75 daysRFA-AI-28-005BiotechLifecycle11 linked GrantNational Institutes of HealthOct 20NIH seeks applications for consortium Translational Centers using Microphysiological Systems for Infectious Diseases (RFA-AI-28-012), with a $7M ceiling.$7M ceilingCloses in 75 daysRFA-AI-28-012BiotechLifecycle14 linked GrantNational Institutes of HealthOct 29NIH seeks applications for Genomic Data Generation Center(s) for the Gabriella Miller Kids First Pediatric Research Program, with a $6 million ceiling and responses due January 8, 2027.$6M ceilingCloses in 54 daysRFA-RM-27-008BiotechLifecycle11 linked